Concepedia

In Vitro and in Vivo Antitumor Effects of Cytotoxic Camptothecin-Bombesin Conjugates Are Mediated by Specific Interaction with Cellular Bombesin Receptors

Terry W. Moody, Lichun Sun, Samuel A. Mantey, Tapas K. Pradhan, L. Vienna Mackey, Nieves Gonzales, Joseph A. Fuselier, David H. Coy, Robert T. Jensen

Journal of Pharmacology and Experimental Therapeutics · 2006 · 59 citations · 32 references

DOI

Concepts

References

32

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Peptide receptor imaging and therapy.

D. J. Kwekkeboom, E. P. Krenning, Marion de Jong · PubMed · 2000 · 330 citations

, , +17

Bombesin receptor subtypes in human cancers: detection with the universal radioligand (125)I-[D-TYR(6), beta-ALA(11), PHE(13), NLE(14)] bombesin(6-14).

Jean Claude Reubi, Sandra Wenger, Jacqueline Schmuckli‐Maurer et al. · PubMed · 2002 · 323 citations

, , +5

CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung.

M A Shipp, George E. Tarr, C Y Chen et al. · Proceedings of the National Academy of Sciences · 1991 · 211 citations

, , +12

Bombesin, bombesin analogs, and related peptides: effects on thermoregulation

Jean Rivier, Marvin R. Brown · Biochemistry · 1978 · 188 citations

, , +6