Concepedia

Generation of a packaging cell line for prolonged large‐scale production of high‐titer HIV‐1‐based lentiviral vector

Yajin Ni, Susan Sun, Ibe Oparaocha, Laurent Humeau, Brian M. Davis, Reuben Cohen, Gwendolyn K. Binder, Yung‐Nien Chang, Vladimir Slepushkin, Boro Dropulić

The Journal of Gene Medicine · 2005 · 77 citations · 42 references

DOI

Abstract

These results demonstrate for the first time HIV-1-based lentiviral vector production on the large scale using a packaging cell line.

References

42

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Negative effect of the transcriptional activator GAL4

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Regulation by HIV Rev depends upon recognition of splice sites

David Chang, Phillip A. Sharp · Cell · 1989 · 516 citations

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A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice.

Penny E. Shockett, Michael J. Difilippantonio, Nathan E. Hellman et al. · Proceedings of the National Academy of Sciences · 1995 · 380 citations · Full text

Position-effect protection and enhancer blocking by the chicken β-globin insulator are separable activities

Félix Recillas‐Targa, Michael J. Pikaart, Bonnie Burgess-Beusse et al. · Proceedings of the National Academy of Sciences · 2002 · 378 citations · Full text

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