Inhibition of SIRT1 Reactivates Silenced Cancer Genes without Loss of Promoter DNA Hypermethylation

Kevin Pruitt, Rebekah L. Zinn, Joyce E. Ohm, +5

PLoS Genetics

Histone ModificationsEpigenetic ChangeGeneticsCancer BiologyEpigenetics +16

Melatonin Promotes Osteoblast Differentiation and Bone Formation

Jerome A. Roth, Byung‐Gook Kim, Wen‐Lang Lin, +1

Journal of Biological Chemistry

Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model

Brittney Jung‐Hynes, Travis L. Schmit, Shannon Reagan‐Shaw, +3

Journal of Pineal Research

Circadian RhythmUrologySirt1 InhibitionEndocrine-related CancerChemoprevention Strategy +11

Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway

Sara C. Zapico, Jezabel Rodríguez‐Blanco, Guillermo García‐Santos, +4

Journal of Pineal Research

Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways

Ning Kang, Jinghai Zhang, Feng Qiu, +3

Cancer Letters

Oxidative Stress CoincidentMedicineApoptosisAutophagyCancer Growth +9

Role of melatonin in cancer treatment.

Antonio Cutando, Antonio López‐Valverde, Salvador Arias‐Santiago, +2

PubMed

Melatonin AloneOncologyAlertnessAgingTumor Microenvironment +12

SIRT1 and c-Myc Promote Liver Tumor Cell Survival and Predict Poor Survival of Human Hepatocellular Carcinomas

Kyu Yun Jang, Sang Jae Noh, Nadja Lehwald, +6

PLoS ONE

C-myc ExpressionImmunologyPathologyCancer BiologyTumor Biology +16

SIRT1-mediated acute cardioprotection

Sergiy M. Nadtochiy, Hongwei Yao, Michael W. McBurney, +4

American Journal of Physiology-Heart and Circulatory Physiology

Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells

Arunasree M. Kalle, Jayasree Badiger, Ali Nakhi, +2

Biochemical and Biophysical Research Communications

Breast OncologyApoptosisBreast Cancer CellsCell DeathBreast Cancer +6

Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer

Lydia Kriegl, Michael Vieth, Thomas Kirchner, +1

Oncotarget