Kevin Pruitt

A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

Joyce E. Ohm, Kelly M. McGarvey, Xiaobing Yu et al. · Nature Genetics · 2007 · 1.1K citations · Full text

Chromatin, Heritable Silencing, Chromatin Structure +14

Inhibition of SIRT1 Reactivates Silenced Cancer Genes without Loss of Promoter DNA Hypermethylation

Kevin Pruitt, Rebekah L. Zinn, Joyce E. Ohm et al. · PLoS Genetics · 2006 · 381 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +18

hTERT Is Expressed in Cancer Cell Lines Despite Promoter DNA Methylation by Preservation of Unmethylated DNA and Active Chromatin around the Transcription Start Site

Rebekah L. Zinn, Kevin Pruitt, Sayaka Eguchi et al. · Cancer Research · 2007 · 203 citations

SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling

Tara N. Calhoun, Madhurima Saxena, Cheynita F. Metoyer et al. · Proceedings of the National Academy of Sciences · 2010 · 109 citations · Full text

Molecular Regulation, Cell Death, Epigenetics +22

Ras-mediated Loss of the Pro-apoptotic Response Protein Par-4 Is Mediated by DNA Hypermethylation through Raf-independent and Raf-dependent Signaling Cascades in Epithelial Cells

Kevin Pruitt, Aylin S. Ülkü, Karen Frantz et al. · Journal of Biological Chemistry · 2005 · 94 citations · Full text