Modulation of multidrug resistance by taxuspine C and other taxoids from Japanese yew

Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones.

Takashi Tsuruo, Harumi Iida-Saito, Hironori Kawabata et al. · PubMed · 1986 · 233 citations

Medicine, Oncology, Pharmacology +15

ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells.

Mikihiko Naito, Hironobu Hamada, T Tsuruo · Journal of Biological Chemistry · 1988 · 142 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Taxuspines A ∼ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells

Jun’ichi Kobayashi, Hirokazu Hosoyama, Hideyuki Shigemori et al. · Tetrahedron · 1994 · 88 citations

Medicine, Medicinal Chemistry, Pharmacology +15

New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells

Iwao Ojima, Pierre‐Yves Bounaud, Craig S. Takeuchi et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 54 citations

Medicine, Oncology, Pharmacology +15

Effects of taxoids from Taxus cuspidata on microtubule depolymerization and vincristine accumulation in MDR cells

Jun’ichi Kobayashi, Hirokazu Hosoyama, Xiaoxia Wang et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 51 citations

Life Sciences, Biochemistry, Cell Biology +12