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Publication | Open Access

Antiplatelet and antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa receptor antagonist.

DOIFull Paper Access

103

Citations

19

References

1994

Year

Shaker A. Mousa, Jeffrey M. Bozarth, Mark S. Forsythe, Sharon M. Jackson, Andrew W. Leamy, Margretta Diemer, Ram P. Kapil, Robert M. Knabb, Michael C. Mayo, S K Pierce
Circulation

Abstract

Acute intravenous DMP 728 administration (0.001 to 1.0 mg/kg) has dose-dependent antiplatelet and antithrombotic effects in different arterial thrombosis models. These data suggest that DMP 728, a low-molecular-weight GPIIb/IIIa receptor antagonist, may have therapeutic potential as an effective antithrombotic agent in coronary and peripheral artery thromboembolic disorders.

References

YearCitations

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