The relationship between urotensin II plasma immunoreactivity and left ventricular filling pressures in coronary artery disease

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

Robert S. Ames, Henry M. Sarau, Johathan K. Chambers et al. · Nature · 1999 · 789 citations

Medicine, Pharmacology, Molecular Pharmacology +5

Congestive heart failure and expression of myocardial urotensin II

Stephen A. Douglas, Lara Tayara, Eliot H. Ohlstein et al. · The Lancet · 2002 · 262 citations

Medicine, Cardiology, Physiology +6

Orphan‐receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin‐1

Janet J. Maguire, Rhoda E. Kuc, Anthony P. Davenport · British Journal of Pharmacology · 2000 · 246 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues

Mika Matsushita, Masayoshi Shichiri, Taihei Imai et al. · Journal of Hypertension · 2001 · 241 citations

Life Sciences, Nephrology, Cell Signaling +8

Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction

Hans‐Peter Nothacker, Zhiwei Wang, Anne Marie McNeill et al. · Nature Cell Biology · 1999 · 238 citations

Medicine, Pharmacology, Physiology +14