Depsipeptide substrates for sortase-mediated N-terminal protein ligation

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.4K citations

Terminal Alkynes, Chemical Engineering, Novel Organocatalysts +12

A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems

Nicholas J. Agard, Jennifer A. Prescher, Carolyn R. Bertozzi · Journal of the American Chemical Society · 2004 · 2.9K citations

Combinatorial Chemistry, Novel Organocatalysts, Bioorganic Chemistry +15

Cell Surface Engineering by a Modified Staudinger Reaction

Eliana Saxon, Carolyn R. Bertozzi · Science · 2000 · 2.4K citations

Tissue Engineering, Bioorganic Chemistry, Engineering +19

<i>Staphylococcus aureus</i> Sortase, an Enzyme that Anchors Surface Proteins to the Cell Wall

Sarkis K. Mazmanian, Gwen Liu, Hung Ton‐That et al. · Science · 1999 · 1K citations

Bacteriology, Bacteriophage, Molecular Biology +18

Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of <i>Staphylococcus aureus</i> at the LPXTG motif

Hung Ton‐That, Gwen Liu, Sarkis K. Mazmanian et al. · Proceedings of the National Academy of Sciences · 1999 · 562 citations · Full text

Biochemistry, Natural Sciences, Medicine +10