Concepedia

7b, a novel naphthalimide derivative, exhibited anti-inflammatory effects via targeted-inhibiting TAK1 following down-regulation of ERK1/2- and p38 MAPK-mediated activation of NF-κB in LPS-stimulated RAW264.7 macrophages

Jin Shao, Yiquan Li, Ziyuan Wang, Mengmeng Xiao, Peihao Yin, Yanhua Lü, Xuhong Qian, Yufang Xu, Jianwen Liu

International Immunopharmacology · 2013 · 79 citations · 29 references

DOI

Concepts

References

29

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IκB: a Specific Inhibitor of the NF-κB Transcription Factor

Patrick A. Baeuerle, David Baltimore · Science · 1988 · 2.2K citations

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The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

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Nitric oxide synthase structure and mechanism

Michael A. Marletta · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

, , +8