Annals of Internal Medicine · 2008 · 618 citations · 43 references
Pain in adults with sickle cell disease is the rule rather than the exception and is far more prevalent and severe than previous large-scale studies have portrayed. It is mostly managed at home; therefore, its prevalence is probably underestimated by health care providers, resulting in misclassification, distorted communication, and undertreatment.
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The Need for a New Medical Model: A Challenge for Biomedicine
George L. Engel · Science · 1977 · 11.8K citations
Orah S. Platt, Bruce D. Thorington, Donald Brambilla et al. · New England Journal of Medicine · 1991 · 1.5K citations · Full text