Concepedia

Cigarette Smoke Suppresses Bik To Cause Epithelial Cell Hyperplasia and Mucous Cell Metaplasia

Yohannes A. Mebratu, Kurt Schwalm, Kevin R. Smith, Mark Schuyler, Yohannes Tesfaigzi

American Journal of Respiratory and Critical Care Medicine · 2011 · 46 citations · 44 references

DOI

Abstract

These studies show that CS suppresses Bik expression to block airway epithelia cell death and thereby increases epithelial cell hyperplasia in chronic bronchitis.

References

44

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, , +15

Combinatorial chemoprevention of intestinal neoplasia

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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

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Endoplasmic reticulum BIK initiates DRP1‐regulated remodelling of mitochondrial cristae during apoptosis

Marc Germain, Jaigi P. Mathai, Heidi M. McBride et al. · The EMBO Journal · 2005 · 329 citations · Full text