Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes

MANIC DEPRESSIVE ILLNESS

Yolande B. Davenport, Marvin L. Adland, Philip W. Gold et al. · The Lancet · 1984 · 2.9K citations

Psychopathology, Psychiatry, Clinical Psychology +11

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

Aging, Mitochondrial Function, Longevity +3

Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science · 2005 · 2.1K citations

Aging, Mitochondrial Function, Mitochondrial Dynamic +12

Manic-depressive illness

Demetrios Papageorgis · Behaviour Research and Therapy · 1991 · 1.5K citations

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

Johannes N. Spelbrink, Fang-Yuan Li, Valeria Tiranti et al. · Nature Genetics · 2001 · 879 citations

Mitochondrial Biogenesis, Mitochondrial Function, Mitochondrial Dynamic +8