Synthetic Vaccines Consisting of Tumor‐Associated MUC1 Glycopeptide Antigens and a T‐Cell Epitope for the Induction of a Highly Specific Humoral Immune Response

Abstract

Selective response: The fully synthetic vaccine shown, which contains a glycopeptide antigen from the tumor-associated mucin MUC1 and an immunostimulating T-cell epitope from ovalbumin, induces a highly specific immune response in mice. The induced antibody reacts with the glycopeptides and analogues that carry additional tumor-associated TN antigen monosaccharides in their sequence.