Plasmodium chabaudi: In vivo effects of Ca2+ antagonists on chloroquine-resistant and chloroquine-sensitive parasites

The multidrug transporter, a double-edged sword.

Michael M. Gottesman, I Pastan · Journal of Biological Chemistry · 1988 · 766 citations · Full text

Life Sciences, Pharmacology, Intracellular Transport +10

Reversal of Chloroquine Resistance in <i>Plasmodium falciparum</i> by Verapamil

Samuel K. Martin, Ayo Oduola, Wilbur K. Milhous · Science · 1987 · 573 citations

Medicine, Infectious Diseases, Pharmacology +17

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

Simon J. Foote, Jennifer K. Thompson, Alan F. Cowman et al. · Cell · 1989 · 569 citations

Life Sciences, Infectious Diseases, Molecular Genetics +16

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

Hiroyuki Hamada, T Tsuruo · Proceedings of the National Academy of Sciences · 1986 · 560 citations · Full text

Medicine, Oncology, Pharmacology +14

Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.

Marilyn M. Cornwell, Ira Pastan, Michael M. Gottesman · Journal of Biological Chemistry · 1987 · 535 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17