Randomised clinical trial: the effect of baclofen in patients with gastro‐oesophageal reflux ‐ a randomised prospective study

Abstract

Baclofen was associated with a significant decrease in percent upright reflux by 24-h pH monitoring and a significant improvement in belching, regurgitation and overall symptom score. Baclofen may be more effective in patients with predominantly upright reflux and belching.