Anticytoplasmic Autoantibodies: Their Immunodiagnostic Value in Wegener Granulomatosis

Abstract

Testing for ACPA in serum of patients with Wegener granulomatosis is valuable for differential diagnosis; furthermore, APCA can be used as a marker to follow disease activity. A new type of ELISA yielded the same results as indirect immunofluorescence for the specificity, sensitivity, and correlation with disease activity of ACPA.