Gold(III)-Catalyzed Double Hydroamination of <i>o</i>-Alkynylaniline with Terminal Alkynes Leading to <i>N</i>-Vinylindoles

Abstract

A highly efficient double-hydroamination reaction of o-alkynylanilines with terminal alkynes leading to N-alkenylindoles was developed by using gold(III) as a catalyst under neat conditions. [reaction: see text].