Gold‐Catalyzed Cyclization of Enynes

Abstract

The key step in the gold-catalyzed cycloisomerization of enynes is the nucleophilic attack at the Au-coordinated CC triple bonds to form a vinylic gold intermediate (see example). The homogeneous gold-catalyzed reaction of enynes under mild conditions has wide scope and high efficiency and gives access to complex or otherwise inaccessible products.