New anti-inflammatory N-pyridinyl(alkyl)phthalimides acting as tumour necrosis factor-α production inhibitors

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

Gerald P. Morris, Paul L. Beck, Margaret S. Herridge et al. · Gastroenterology · 1989 · 1.7K citations

Life Sciences, Immunology, Physiology +16

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

Terje Espevik · Journal of Immunological Methods · 1986 · 1.3K citations

Life Sciences, Cell Biology, Immunology +7

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

E P Sampaio, Euzenir Nunes Sarno, Ruth Galilly et al. · The Journal of Experimental Medicine · 1991 · 1.2K citations · Full text

Medicine, Immunology, Pharmacology +14

Tumour necrosis factor α and interleukin 1β in relapse of Crohn's disease

Stefan Schreiber, Susanna Nikolaus, Jochen Hampe et al. · The Lancet · 1999 · 251 citations

Veterinary Medicine, Immunology, Pathobiology +14

Structural Modifications of Thalidomide Produce Analogs with Enhanced Tumor Necrosis Factor Inhibitory Activity

George W. Muller, Laura G. Corral, Mary G. Shire et al. · Journal of Medicinal Chemistry · 1996 · 157 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9