Concepedia

Inhibition of dihydrofolate reductase from bacterial and vertebrate sources by folate, aminopterin, methotrexate and their 5-deaza analogues

Stuart R. Stone, John A. Montgomery, John F. Morrison

Biochemical Pharmacology · 1984 · 51 citations · 20 references

DOI

Concepts

References

20

Data for biochemical research

Comparative Biochemistry and Physiology Part A Physiology · 1987 · 3K citations

, , +5

Data for Biochemical Research.

Annals of Internal Medicine · 1969 · 1.3K citations

, , +7

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

J.T. Bolin, David J. Filman, David A. Matthews et al. · Journal of Biological Chemistry · 1982 · 745 citations · Full text

, , +17

Tight-binding inhibitors—I

Sungman Cha · Biochemical Pharmacology · 1975 · 503 citations

The slow-binding and slow, tight-binding inhibition of enzyme-catalysed reactions

John F. Morrison · Trends in Biochemical Sciences · 1982 · 495 citations

, , +14