The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor <i>Foxp3 </i>

WanJun Chen, Wenwen Jin, Neil J. Hardegen et al. · The Journal of Experimental Medicine · 2003 · 4.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

Marcia M. Shull, Ilona Ormsby, Ann B. Kier et al. · Nature · 1992 · 3K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

A B Kulkarni, C G Huh, Daniel M. Becker et al. · Proceedings of the National Academy of Sciences · 1993 · 2K citations

Life Sciences, Immunology, Pathology +16

Epigenetic Control of the foxp3 Locus in Regulatory T Cells

Stefan Floess, Jennifer Freyer, Christiane Siewert et al. · PLoS Biology · 2007 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

Yongqing Wu, Madhuri Borde, Vigo Heissmeyer et al. · Cell · 2006 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +10