XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4K citations · Full text

Transcriptional Regulation, Signal Transduction, Molecular Regulation +9

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.2K citations

Protein Function, Signal Transduction, Protein Folding +6

Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

Heather P. Harding, Isabel Novoa, Yuhong Zhang et al. · Molecular Cell · 2000 · 3.2K citations · Full text

Transcriptional Regulation, Developmental Biology, Cell Regulation +7

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

Marcella A. Calfon, Huiqing Zeng, Fumihiko Urano et al. · Nature · 2002 · 2.8K citations

Protein Secretion, Signal Transduction, Xbp-1 Mrna +12

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher · Molecular and Cellular Biology · 2003 · 2K citations · Full text