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Debut and Accumulation of Centric Fusion Products: An Index to Age of Certain Cell Lines
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1967
Year
CytogeneticsGeneticsDog Cell LineCell CultureCell ProliferationCell CycleReproductive BiologyCell SpecializationAnimal GeneticsEmbryologyMembrane FusionPublic HealthBos TaurusCell DivisionFourteen Cell LinesCentric Fusion ProductsGenetic VariationChromosomal RearrangementCell EngineeringCell BiologyCertain Cell LinesBiologyAnimal ReproductionChromosome DynamicsDevelopmental BiologyAnimal ScienceVeterinary ScienceCellular SenescenceChromosome BiologyMedicine
Fourteen cell lines derived from cattle (<i>Bos taurus</i>), sheep (<i>Ovis arks</i>), goat (<i>Capra hircus</i>) and dog (<i>Canis familiaris</i>) were studied at various passage levels and compared chromosomally. Of these lines, those derived from the three species of Bovidae showed a similar pattern in acquisition, maintenance and increase in numbers of unusual atelocentric chromosomes with passages <i>in vitro, </i>while the dog cell line appeared to follow a different pattern.