The human X-linked steroid sulfatase gene and a Y-encoded pseudogene: Evidence for an inversion of the Y chromosome during primate evolution

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

W. David Benton, Ronald W. Davis · Science · 1977 · 4.7K citations

Life Sciences, Genetics, Molecular Biology +8

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

Mark D. Biggin, Toby J. Gibson, G. F. Hong · Proceedings of the National Academy of Sciences · 1983 · 2.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

Richard M. Lawn, Edward F. Fritsch, Richard C. Parker et al. · Cell · 1978 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +5

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man

Haig H. Kazazian, Corinne Wong, Hagop Youssoufian et al. · Nature · 1988 · 928 citations

Life Sciences, Genetics, Molecular Genetics +4