Science · 1979 · 157 citations · 17 references
Life SciencesImmunologyPharmacologyCalcium HomeostasisCell SignalingSignal TransductionCalcium MetabolismCalcium SignalingIntracellular Calcium SignalingLeukocyte RecruitmentNeutrophil BiologyCalcium Influx MechanismsCalcium Release From Intracellular StoresCalcium TransportCalcium-induced Calcium ReleaseCalcium-mediated SignalingChemotactic MediatorsChemotactic SignalingCytosolic Calcium Signaling
The interaction of chemotactic factors (fMet-Leu-Phe and C5a) with rabbit neutrophils leads to rapid and specific release of membrane calcium, as evidenced by changes in the fluorescence of cell-associated chlorotetracycline. These two structurally different stimuli appear to interact with the same pool of membrane calcium.
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