Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis

References

Page 1

	Year	Citations
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene David C. Whitcomb, Michael C. Gorry, Robert A. Preston, Nature Genetics Pancreatic CancerPancreatic Fluid CollectionGeneticsPathogenesisGastroenterology	1996	1.6K
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis Heiko Witt, W. A. P. Luck, Hans Christian Hennies, Nature Genetics Chronic PancreatitisPancreatic CancerPancreatic Fluid CollectionImmunologyGastroenterology	2000	1K
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis Roland H. Pfützer, M. Michael Barmada, Andrew P. J. Brunskill, Gastroenterology Pancreatic Fluid CollectionGeneticsGenetic EpidemiologyGastroenterologyPathology	2000	514
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis MC Gorry, D Gabbaizedeh, William Furey, Gastroenterology Chronic PancreatitisPancreatic CancerGeneticsPathogenesisGastroenterology	1997	476
A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis Heiko Witt, W. A. P. Luck, Michael Becker Gastroenterology Chronic PancreatitisSignal TransductionMedicinePathogenesisImmunology	1999	260
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis Heiko Witt, Miklós Sahin‐Tóth, Olfert Landt, Nature Genetics Pancreatic CancerPancreatic Fluid CollectionImmunologyGastroenterologyPathology	2006	248
Tropical calcific pancreatitis: Strong association with SPINK1 trypsin inhibitor mutations Eesh Bhatia, Gourdas Choudhuri, Sadiq S. Sikora, Gastroenterology Pancreatic CancerTropical Calcific PancreatitisImmunologyGastroenterologyPathology	2002	214
Hereditary pancreatitis caused by triplication of the trypsinogen locus Cédric Le Maréchal, Emmanuelle Masson, Jian‐Min Chen, Nature Genetics Genetic DisorderPancreatic Fluid CollectionGeneticsPathogenesisHistopathology	2006	203
Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme Y Richárd Szmola, Miklós Sahin‐Tóth Proceedings of the National Academy of Sciences ImmunologyChymotrypsin CPeptide ScienceGastrointestinal Peptide HormoneTrypsin Degradation	2007	166
SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh Alexander Schneider, Amitabh Suman, Livio Rossi, Gastroenterology Pancreatic CancerGlobal HealthDiabetesGenetic EpidemiologyGenetics	2002	155

Page 1