A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

David C. Whitcomb, Michael C. Gorry, Robert A. Preston et al. · Nature Genetics · 1996 · 1.6K citations

Medicine, Genetics, Molecular Genetics +12

Mutations of the Cystic Fibrosis Gene in Patients with Chronic Pancreatitis

NICHOLAS H. SHARER, Martin Schwarz, Geraldine Malone et al. · New England Journal of Medicine · 1998 · 963 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Relation between Mutations of the Cystic Fibrosis Gene and Idiopathic Pancreatitis

Jonathan Cohn, Kenneth J. Friedman, Peadar G. Noone et al. · New England Journal of Medicine · 1998 · 930 citations

Medicine, Genetics, Molecular Genetics +16

Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis

MC Gorry, D Gabbaizedeh, William Furey et al. · Gastroenterology · 1997 · 476 citations · Full text

Medicine, Genetics, Molecular Genetics +7

The Complete 685-Kilobase DNA Sequence of the Human β T Cell Receptor Locus

Lee Rowen, Ben F. Koop, Leroy Hood · Science · 1996 · 438 citations

Life Sciences, Genetics, Immunology +17