Concepedia

The mechanism of Z α1-antitrypsin accumulation in the liver

David A. Lomas, Dyfed LI-Evans, J.T. Finch, Robin W. Carrell

Nature · 1992 · 1.1K citations · 10 references

DOI

Concepts

References

10

The Electrophoretic α; <sub>1</sub> -Globulin Pattern of Serum in α; <sub>1</sub> -Antitrypsin Deficiency

C.‐B. Laurell, Sten Eriksson · Scandinavian Journal of Clinical and Laboratory Investigation · 1963 · 1.4K citations

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Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice.

Joyce Carlson, Brianne B. Rogers, R N Sifers et al. · Journal of Clinical Investigation · 1989 · 329 citations · Full text

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Mobile reactive centre of serpins and the control of thrombosis

Robin W. Carrell, Dyfed L. Evans, Penelope E. Stein · Nature · 1991 · 301 citations

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Structural transition of α<sub>1</sub>‐antitrypsin by a peptide sequentially similar to β‐strand s4A

Andreas J. Schulze, Ulrich Baumann, S Knof et al. · European Journal of Biochemistry · 1990 · 197 citations · Full text

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Soluble aggregates of the human PiZ alpha 1-antitrypsin variant are degraded within the endoplasmic reticulum by a mechanism sensitive to inhibitors of protein synthesis.

A. Le, G.A. Ferrell, D S Dishon et al. · Journal of Biological Chemistry · 1992 · 129 citations · Full text

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