Failed interleukin-6 signal transduction in murine sepsis: Attenuation of hepatic glycoprotein 130 phosphorylation - Concepedia

Concepedia

Publication | Open Access

Failed interleukin-6 signal transduction in murine sepsis: Attenuation of hepatic glycoprotein 130 phosphorylation

DOI Full Paper Access

26

Citations

24

References

2009

Year

Arnoley S. Abcejo, Kenneth M. Andrejko, Nichelle Raj, Clifford S. Deutschman

Critical Care Medicine

Abstract

Impaired gp130 phosphorylation may be responsible for IL-6 hyporesponsiveness during sepsis.

References

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Sepsis-Induced Apoptosis Causes Progressive Profound Depletion of B and CD4+ T Lymphocytes in Humans Richard S. Hotchkiss, Kevin W. Tinsley, Paul E. Swanson, The Journal of Immunology	2001	914
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Six at Six: Interleukin-6 Measured 6 H After the Initiation of Sepsis Predicts Mortality Over 3 Days Daniel G. Remick, Gerald R. Bolgos, Javed Siddiqui, Shock	2002	438
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SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130 Jochen Schmitz, Manuela Weißenbach, Serge Haan, Journal of Biological Chemistry	2000	391

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