Ultraviolet laser ablation of skin: Healing studies and a thermal model

Abstract

We have followed the course of healing of incisions made with the krypton-fluoride excimer laser. Incisions were made in guinea pig skin, in vivo, under identical conditions of irradiation. The progressive healing of these incisions was followed over the course of 3 weeks. We noted excellent healing with re-epithelialization, and the re-formation of collagen fibers with minimal fibrosis. We present a simple thermal model for ablation of tissue by a short pulse of strongly absorbed laser radiation.