Concepedia

Epoxy amino acids produced from allylglycines intramolecularly cyclised to yield four stereoisomers of 4-hydroxyproline derivatives

Suvratha Krishnamurthy, Toru Arai, Kanae Nakanishi, Norikazu Nishino

RSC Advances · 2013 · 15 citations · 32 references

DOI

Concepts

Abstract

Intermolecular epoxide-opening generated stereoisomeric hydroxyprolines; cis -isomer formed lactone, being easily separable from trans -hydroxyproline ester.

References

32

Kinetic resolution of unnatural and rarely occurring amino acids: enantioselective hydrolysis of N-acyl amino acids catalyzed by acylase I

H. Keith Chenault, Juergen Dahmer, George M. Whitesides · Journal of the American Chemical Society · 1989 · 308 citations

, , +12

Proline Editing: A General and Practical Approach to the Synthesis of Functionally and Structurally Diverse Peptides. Analysis of Steric versus Stereoelectronic Effects of 4-Substituted Prolines on Conformation within Peptides

Anil K. Pandey, Devan Naduthambi, Krista Thomas et al. · Journal of the American Chemical Society · 2013 · 177 citations

, , +15

Efficient Large-Scale Synthesis of BILN 2061, a Potent HCV Protease Inhibitor, by a Convergent Approach Based on Ring-Closing Metathesis

Nathan K. Yee, Vittorio Farina, Ioannis N. Houpis et al. · The Journal of Organic Chemistry · 2006 · 159 citations

, , +11

Fast, efficient and selective deprotection of the <i>tert</i>‐butoxycarbonyl (Boc) group using HCl/dioxane (4 <scp>m</scp>)

G. Han, Makoto Tamaki, Victor J. Hruby · Journal of Peptide Research · 2001 · 151 citations

, , +14

Identification and Characterization of the Echinocandin B Biosynthetic Gene Cluster from Emericella rugulosa NRRL 11440

Ralph A. Cacho, Wei Jiang, Yit‐Heng Chooi et al. · Journal of the American Chemical Society · 2012 · 144 citations · Full text

, , +17