Interaction of the Nuclear Matrix Protein NAKAP With HypA and Huntingtin: Implications for Nuclear Toxicity in Huntington's Disease Pathogenesis

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

Life Sciences, Neurobiology, Neuroscience +16

Neuropathological Classification of Huntingtonʼs Disease

Jean‐Paul Vonsattel, Richard H. Myers, Thomas J. Stevens et al. · Journal of Neuropathology & Experimental Neurology · 1985 · 2.6K citations

Medicine, Neurology, Neuroscience +17

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

Life Sciences, Genetics, Neurology +17

Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity

Frederick C. Nucifora, Masayuki Sasaki, Matthew F. Peters et al. · Science · 2001 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +16

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +17