Dominant Role of the sst1 Locus in Pathogenesis of Necrotizing Lung Granulomas during Chronic Tuberculosis Infection and Reactivation in Genetically Resistant Hosts

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

Laura E. Via, Philana Ling Lin, Sonja M. Ray et al. · Infection and Immunity · 2008 · 649 citations · Full text

Medicine, Infectious Diseases, Pathology +17

Virulence of a <i>Mycobacterium tuberculosis</i> clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β

Claudia Manca, Liana Tsenova, Amy Bergtold et al. · Proceedings of the National Academy of Sciences · 2001 · 601 citations · Full text

Veterinary Medicine, Immunology, Microbiology +17

Global tuberculosis control: surveillance planning financing. WHO report 2008.

Christopher Dye, Katherine Floyd, M Uplekar · 2008 · 568 citations

Public Health, Infectious Disease Control, Infectious Diseases +16

Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis.

Amy Myers Caruso, Natalya V. Serbina, Edwin Klein et al. · PubMed · 1999 · 496 citations

Life Sciences, Immunology, Infectious Diseases +17

Ipr1 gene mediates innate immunity to tuberculosis

Hui Pan, Bo‐Shiun Yan, Mauricio Rojas et al. · Nature · 2005 · 493 citations · Full text

Life Sciences, Immunology, Molecular Biology +12