Ipr1 gene mediates innate immunity to tuberculosis

The primary mechanism of attenuation of bacillus Calmette–Guérin is a loss of secreted lytic function required for invasion of lung interstitial tissue

Tsungda Hsu, Suzie Hingley‐Wilson, Bing Chen et al. · Proceedings of the National Academy of Sciences · 2003 · 739 citations · Full text

Veterinary Medicine, Infectious Diseases, Microbiology +12

Individual RD1‐region genes are required for export of ESAT‐6/CFP‐10 and for virulence of <i>Mycobacterium tuberculosis</i>

Kristi M. Guinn, Mark J. Hickey, Sanjeev Kumar Mathur et al. · Molecular Microbiology · 2004 · 517 citations · Full text

Life Sciences, Genetics, Microbiology +16

Genetic control of resistance to experimental infection with virulent <i>Mycobacterium tuberculosis</i>

Igor Kramnik, William F. Dietrich, Peter Démant et al. · Proceedings of the National Academy of Sciences · 2000 · 356 citations · Full text

Life Sciences, Genetics, Infectious Diseases +15

Genetic susceptibility to tuberculosis in Africans: A genome-wide scan

Richard Bellamy, Nulda Beyers, Keith P. W. J. McAdam et al. · Proceedings of the National Academy of Sciences · 2000 · 308 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

The Nuclear Dot Protein Sp100, Characterization of Domains Necessary for Dimerization, Subcellular Localization, and Modification by Small Ubiquitin-like Modifiers

Thomas Sternsdorf, Kirsten Jensen, Berthold Reich et al. · Journal of Biological Chemistry · 1999 · 264 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17