Concepedia

The Effect of Increasing Control-to-case Ratio on Statistical Power in a Simulated Case-control SNP Association Study

Moonsu Kang, Sun-Hee Choi, InSong Koh

Genomics & Informatics · 2009 · 48 citations · 9 references

DOIFull text

Open access

Concepts

Abstract

Decision (H0) Reject Not reject H0 True (Type error, false positive) 1- False (=H1) 1- (Power) (Type error, false negative)

References

9

PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

Shaun Purcell, Benjamin M. Neale, Katherine EO Todd-Brown et al. · The American Journal of Human Genetics · 2007 · 36.1K citations · Full text

, , +13

Power and sample size calculations

William D. Dupont, W. Dale Plummer · Controlled Clinical Trials · 1990 · 2.1K citations

, , +11

Genetic Power Calculator: design of linkage andassociation genetic mapping studies of complex traits

Shaun Purcell, Stacey S. Cherny, Pak C. Sham · Bioinformatics · 2002 · 2.1K citations · Full text

, , +17

Factors Influencing the Optimal Control-to-Case Ratio in Matched Case-Control Studies

Sean Hennessy, Warren B. Bilker, J A Berlin et al. · American Journal of Epidemiology · 1999 · 349 citations · Full text

, , +16

Power Calculations for Matched Case-Control Studies

William D. Dupont · Biometrics · 1988 · 335 citations

, , +16