Rosiglitazone and Gemcitabine in combination reduces immune suppression and modulates T cell populations in pancreatic cancer

Differentiation and reversal of malignant changes in colon cancer through PPARγ

Pasha Sarraf, Elisabetta Mueller, Daniel M. Jones et al. · Nature Medicine · 1998 · 973 citations

Medicine, Molecular Biology, Oncology +12

Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions

Nobuyoshi Hiraoka, Kaoru Onozato, Tomoo Kosuge et al. · Clinical Cancer Research · 2006 · 822 citations

Medicine, Immunology, Oncology +17

A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response

Chinyu Su, Xiaoming Wen, Shannon T. Bailey et al. · Journal of Clinical Investigation · 1999 · 758 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Prostaglandin E2 Promotes Tumor Progression by Inducing Myeloid-Derived Suppressor Cells

Pratima Sinha, Virginia K. Clements, Amy M. Fulton et al. · Cancer Research · 2007 · 741 citations · Full text

Medicine, Immunology, Oncology +17

Inflammation Induces Myeloid-Derived Suppressor Cells that Facilitate Tumor Progression

Stephanie K. Bunt, Pratima Sinha, Virginia K. Clements et al. · The Journal of Immunology · 2006 · 529 citations · Full text

Medicine, Immunology, Oncology +17