Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: An insight into endotoxin shock

Characterization of three inhibitors of endothelial nitric oxide synthase <i>in vitro</i> and <i>in vivo</i>

Daryl D. Rees, Richard Palmer, Richard Schulz et al. · British Journal of Pharmacology · 1990 · 1.9K citations · Full text

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Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

Michael A. Marletta, Poksyn S. Yoon, Radha Iyengar et al. · Biochemistry · 1988 · 1.6K citations

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L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.4K citations

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L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

John B. Hibbs, Zdenek Vavrin, Read R. Taintor · The Journal of Immunology · 1987 · 937 citations · Full text

Life Sciences, Immunology, Pharmacology +13

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

Daryl D. Rees, Richard Palmer, H. F. Hodson et al. · British Journal of Pharmacology · 1989 · 856 citations · Full text

Medicine, Pharmacology, Physiology +14