Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Aβ

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

Life Sciences, Neurology, Neuroscience +14

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations

Life Sciences, Neurology, Neuroscience +17

Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

Dave Morgan, David M. Diamond, Paul E. Gottschall et al. · Nature · 2000 · 1.5K citations

Life Sciences, Immunology, Neuroscience +12

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

Christopher Janus, Jacqueline Pearson, JoAnne McLaurin et al. · Nature · 2000 · 1.4K citations

Life Sciences, Neurobiology, Neuroscience +14

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

Ronald B. DeMattos, Kelly R. Bales, David J. Cummins et al. · Proceedings of the National Academy of Sciences · 2001 · 1.3K citations · Full text

Pharmacy, Neurobiology, Neuroscience +17