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Substrate Filtering by the Active Site Crossover Loop in UCHL3 Revealed by Sortagging and Gain-of-function Mutations

Protein AssemblyProtein FoldingNatural SciencesSubstrate FilteringProtein X-ray CrystallographyMolecular BiologyMolecular GeneticsGain-of-function MutationsBiomolecular InteractionSystems BiologyMedicineMulti-protein AssemblyUchl3 RevealedStructural BiologyMutagenesis