The effect of tuberculin on sensitized and normal leucocytes

Abstract

It has been shown that the cells in exudates produced by the injection of tuberculin into the serous cavities of sensitized animals are alive and not dead as claimed previously. Such cells consumed oxygen and glucose at the same rate as cells obtained similarly from normal animals but moved somewhat less actively. Purified tuberculin had no specific effect on the respiration in vitro of macrophages or neutrophil leucocytes derived from sensitized animals.