Biopharmaceutical characterization of oral immediate release drug products. In vitro/in vivo comparison of phenoxymethylpenicillin potassium, glimepiride and levofloxacin

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

HT29-MTX/Caco-2 Cocultures as an in Vitro Model for the Intestinal Epithelium: In Vitro–in Vivo Correlation with Permeability Data from Rats and Humans

Elke Walter, Sonia L. Janich, Blake J. Roessler et al. · Journal of Pharmaceutical Sciences · 1996 · 269 citations

Life Sciences, Cell Biology, Pharmacology +15

Estimating the Fraction Dose Absorbed from Suspensions of Poorly Soluble Compounds in Humans: A Mathematical Model

Doo‐Man Oh, Rane L. Curl, Gordon L. Amidon · Pharmaceutical Research · 1993 · 247 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +15

Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier

Glynn Wilson, Ian F. Hassan, C. J. Dix et al. · Journal of Controlled Release · 1990 · 242 citations

Life Sciences, Cell Biology, Physiology +14