The Angiotensin II Type 1 Receptor Gene Polymorphism Is Associated With Coronary Artery Vasoconstriction

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

Marcus A. DeWood, Julie Spores, Robert N. Notske et al. · New England Journal of Medicine · 1980 · 2.7K citations

Medicine, Cardiology, Internal Medicine +12

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

François Cambien, Odette Poirier, Laure Lecerf et al. · Nature · 1992 · 1.9K citations

Medicine, Genetics, Molecular Genetics +14

Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?

William C. Little, M Constantinescu, Robert J. Applegate et al. · Circulation · 1988 · 1.5K citations

Medicine, Cardiology, Cardiothoracic Radiology +14

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

Laurence Tiret, Brigitte Rigat, C Breda et al. · PubMed · 1992 · 1.2K citations

Medicine, Genetics, Molecular Genetics +6