Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

Valentı́n Fuster · New England Journal of Medicine · 1992 · 3.7K citations

Medicine, Cardiology, Nuclear Medicine +12

The world health organization monica project (monitoring trends and determinants in cardiovascular disease): A major international collaboration

WHO MONICA Project Principal Invest · Journal of Clinical Epidemiology · 1988 · 1.8K citations

Public Health, Cardiology, Preventive Medicine +16

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

Brigitte Rigat, Christine Hübert, Pierre Corvol et al. · Nucleic Acids Research · 1992 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

Laurence Tiret, Brigitte Rigat, C Breda et al. · PubMed · 1992 · 1.2K citations

Medicine, Genetics, Molecular Genetics +6