Saccadic eye movement deficits in the MPTP monkey model of Parkinson's disease

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

J. William Langston, Philip L. Ballard, James W. Tetrud et al. · Science · 1983 · 4.9K citations

Life Sciences, Neuroscience, Pharmacology +14

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

Glenn C. Davis, Adrian Williams, Sanford P. Markey et al. · Psychiatry Research · 1979 · 1.4K citations

Medicine, Neurology, Pharmacology +16

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

J. William Langston, Lysia S. Forno, Charles S. Rebert et al. · Brain Research · 1984 · 919 citations

Medicine, Pharmacology, Toxicology +5

Visual and oculomotor functions of monkey substantia nigra pars reticulata. IV. Relation of substantia nigra to superior colliculus

Okihide Hikosaka, R. H. Wurtz · Journal of Neurophysiology · 1983 · 818 citations

Life Sciences, Neurobiology, Neuroscience +16