Concepedia

Generation of Novel AAV Variants by Directed Evolution for Improved CFTR Delivery to Human Ciliated Airway Epithelium

Wuping Li, Liqun Zhang, Jarrod S. Johnson, Zhijian Wu, Joshua C. Grieger, Ping‐Jie Xiao, Lauren M. Drouin, Mavis Agbandje‐McKenna, Raymond J. Pickles, R. Jude Samulski

Molecular Therapy · 2009 · 85 citations · 39 references

DOIFull text

Open access

Concepts

References

39

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

, , +16

SWISS-MODEL: an automated protein homology-modeling server

Torsten Schwede · Nucleic Acids Research · 2003 · 5.7K citations · Full text

, , +15

Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

Xiao Xiao, Juan Li, R. Jude Samulski · Journal of Virology · 1998 · 1.4K citations · Full text

, , +10

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

Nicholas C. Jones, Thomas Shenk · Cell · 1979 · 785 citations

, , +10

Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity

Joseph E. Rabinowitz, Fabienne Rolling, Chengwen Li et al. · Journal of Virology · 2002 · 750 citations · Full text

, , +14