Non-proteinogenic amino acid synthesis. The β-anion derived from aspartic acid, and its application to α-amino acid synthesis.

.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

James A. Dale, David L. Dull, Harry S. Mosher · The Journal of Organic Chemistry · 1969 · 2.5K citations

Natural Sciences, Chemistry, Analytical Chemistry +6

The invention of new radical chain reactions. Part VIII. Radical chemistry of thiohydroxamic esters; A new method for the generation of carbon radicals from carboxylic acids

Derek H. R. Barton, David Crich, William B. Motherwell · Tetrahedron · 1985 · 528 citations

Natural Sciences, Chemistry, Organic Chemistry +11

Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality

Dieter Seebàch, M. BOES, Reto Naef et al. · Journal of the American Chemical Society · 1983 · 390 citations

Natural Sciences, Biochemistry, Chemistry +15

Stereoselective amination of chiral enolates. A new approach to the asymmetric synthesis of .alpha.-hydrazino and .alpha.-amino acid derivatives

David A. Evans, Thomas C. Britton, Roberta L. Dorow et al. · Journal of the American Chemical Society · 1986 · 237 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Practical asymmetric syntheses of .alpha.-amino acids through carbon-carbon bond constructions on electrophilic glycine templates

Robert M. Williams, D. ZHAI · Journal of the American Chemical Society · 1988 · 228 citations

Natural Sciences, Biochemistry, Chemistry +12