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Sleep Apnea as Part of a Sequence of Events: A Comparison of Three Months Old Infants at Low and Increased Risk for Sudden Infant Death Syndrome (SIDS)
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References
1978
Year
Physiological EventsSleep DisordersNeonatologyBreathing DisordersPediatric Lung DiseaseSleep-related Breathing DisorderSleep MedicineObstructive Sleep ApneaCentral OriginSleepNear Miss InfantsNewborn MedicineInfant CognitionSleep Disordered BreathingChild DevelopmentSleep DisorderPediatricsSleep ApneaMedicineEmergency MedicineAnesthesiology
Physiological events leading to and following sleep apnea (≥ 6 seconds) of central origin were examined in three months old infants at low and increased risk for Sudden Infant Death Syndrome (SIDS). These included nine control infants, nine subsequent siblings of SIDS and seven infants with unexplained apnea and transient cyanosis requiring intervention (“near miss” for SIDS). Each minute of twelve hour recordings of EEG, eye movements, somatic activity, respiration, ECG and temperature was coded into Active Sleep (AS), Quiet Sleep (QS), Indeterminate (IN) and Awake (AW). One hundred and sixty-one apnea were identified in control infants, 68 in subsequent siblings and 144 in near miss infants. The between subject variability was large in all three groups. These apnea were submitted to a detailed computer analysis which provided data on somatic activity, heart rate and respiratory patterns preceding and following each apnea.