Vaccine Development and Therapy · 2014 · 38 citations · 149 references
Veterinary MedicineInfectious DiseasesVeterinary ParasitologyParasitologyVaccinologyVeterinary Parasitic DiseasesParasite ControlParasitic Disease PathogenesisParasitic Disease PreventionProtozoan ZoonosesVeterinary VaccinationVeterinary VaccinesCurrent Control StrategiesPathogen-host InteractionsToxoplasma Gondii ProphylaxisToxoplasmosis EpidemiologyToxoplasmosis PathogenesisToxoplasmosis PreventionToxoplasmosis TreatmentToxoplasmosis Vaccines
Abstract: Toxoplasma gondii is an intracellular protozoan parasite that can infect many warm-blooded animal species and humans. Despite substantial knowledge of the biology, epidemiology, and host-pathogen interactions of T. gondii , there are still very few effective control strategies to prevent oocyst shedding in cats, tissue cysts in livestock for consumption, and infection and disease in humans. This article reviews current progress and targets for vaccination against T. gondii . Keywords: toxoplasmosis, vaccination, livestock animals, cats, immune response, organelles
149
Initial sequencing and comparative analysis of the mouse genome