Publication | Closed Access
Chemical Development of NBI-75043. Use of a Flow Reactor to Circumvent a Batch-Limited Metal−Halogen Exchange Reaction
33
Citations
15
References
2008
Year
Chemical KineticsEngineeringChemical DevelopmentChemistryChemical EngineeringIndustrial ChemistryDiscovery RouteMetabolic EngineeringTraditional Batch ChemistryFlow ReactorInorganic ChemistryFlow ChemistryFlow SynthesisCatalysisCatalytic ProcessReaction EngineeringKey ReactionReaction ProcessProcess Chemistry
The discovery route and subsequent scale-up routes for NBI-75043 are presented. When traditional batch chemistry was found to limit the scale of a key reaction, a flow reactor was designed and optimized to provide an alternate method of production.
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