Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

Peter Vaupel, F. Kallinowski, Paul Okunieff · PubMed · 1989 · 3.4K citations

Tumor Innervation, Biological Microenvironments, Pathology +20

Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation

Gabriel Helmlinger, Fan Yuan, Marc Dellian et al. · Nature Medicine · 1997 · 1.6K citations

Cancer Research, Interstitial Ph, Perineural Invasion +9

Tumor development under angiogenic signaling: a dynamical theory of tumor growth, treatment response, and postvascular dormancy.

Philip Hahnfeldt, Dipak Panigrahy, Judah Folkman et al. · PubMed · 1999 · 668 citations

Dynamic Balance, Tumor Biology, Angiogenesis +17

Recent trends and important developments in propolis research

Vassya Bankova · Evidence-based Complementary and Alternative Medicine · 2004 · 558 citations · Full text

Biology, Medicinal Chemistry, Propolis Pharmacological Research +14

Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy.

Kunihiko Izuishi, Kazuyoshi Kato, Tsutomu Ogura et al. · PubMed · 2000 · 353 citations

Chemoprevention Strategy, Apoptosis, Pathology +18